Carine Giovannangeli

This study identifies that loss of Polθ reduces unwanted mutations in zebrafish prime editing, enabling error-free and efficient genome editing.

This paper describes a prime editing strategy to modify γ-globin promoters in HSPCs to increase HbF expression for sickle cell disease treatment.

The paper identifies a novel tardigrade-specific DNA binding protein, TDR1, that enhances resistance to ionizing radiation in human cells.

This paper introduces a near PAM-less base editor that enables efficient point mutation introduction in zebrafish for disease modeling.