Marie As

This paper introduces TILV, a CRISPR-assisted method for precise targeted integration of transgenes in human hematopoietic stem cells using IDLV donors, showing improved efficiency and minimal impact on cell viability.

This study identifies that loss of Polθ reduces unwanted mutations in zebrafish prime editing, enabling error-free and efficient genome editing.

The paper compares CRISPR/Cas9 gene editing efficiency in retinal organoids, HEK293T cells, and mouse models, finding retinal organoids better mirror in vivo editing outcomes.

The paper identifies a novel tardigrade-specific DNA binding protein, TDR1, that enhances resistance to ionizing radiation in human cells.