Lorenzo Tomassoni

Identification and Targeting of Regulators of SARS-CoV-2-Host Interactions in the Airway Epithelium.

The paper identifies master regulator modules in human airway epithelial cells reprogrammed by SARS-CoV-2 and finds 11 drugs that reverse these signatures.

Elucidation and Pharmacologic Targeting of Master Regulator Dependencies in Coexisting Diffuse Midline Glioma Subpopulations

The paper identifies master regulator dependencies in coexisting diffuse midline glioma subpopulations and shows that combination therapy targeting these regulators improves survival in vivo.

A new Bayesian methodology for nonlinear model calibration in Computational Systems Biology

This paper introduces a Bayesian method for nonlinear model calibration using omics data, showing it outperforms existing methods in robustness and computational efficiency.

Conditional Robust Calibration (CRC): a new computational Bayesian methodology for model parameters estimation and identifiability analysis

This paper introduces a Bayesian method for model calibration and identifiability analysis, showing it provides more robust and precise results than existing approaches.