A horizontally acquired cyclic di-GMP phosphodiesterase regulated by zinc and quorum sensing
Aathmaja Anandhi Rangarajan, Kiwon Ok, Marissa K. Malleck, Micah J. Ferrell, Thomas V. O’Halloran, Christopher M. Waters
This paper identifies and characterizes ZpdA, a zinc-regulated phosphodiesterase in V. cholerae that modulates cyclic di-GMP levels through transcriptional and post-translational zinc dependence.
bioRxiv · Apr 25, 2025 · PreprintMicrobiology