Aathmaja Anandhi Rangarajan

This study investigates the dual-function DGC/PDE DcpB in A. tumefaciens, showing its cell cycle-dependent PDE activity regulates motility and biofilm formation, with genetic interactions involving thuR.

The paper identifies Gp15, a phage DNA ejection protein that inhibits the CBASS effector CapV to evade bacterial antiviral defense.

This paper identifies and characterizes ZpdA, a zinc-regulated phosphodiesterase in V. cholerae that modulates cyclic di-GMP levels through transcriptional and post-translational zinc dependence.

This study shows that negative feedback of c-di-GMP levels in V. cholerae optimizes switching between sessile and motile lifestyles by regulating PDE expression through VpsR.