Author

Tobias Bock

Mortimer B. Zuckerman Mind Brain Behavior InstituteORCID 0000-0002-7734-1183Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:electronic health records· 2

Frequent Co-Authors

Steven A. SiegelbaumiD· 3 shared Bina SantoroiD· 2 shared Eric W. BussiD· 2 shared Félix LeroyiD· 2 shared Adrian NegreaniD· 1 shared Alessandro PorroiD· 1 shared Anastasia Barnett· 1 shared Andrea MerseburgiD· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersNeuroscience

Steven A. SiegelbaumORCID

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3 papers

Recent·Most cited

The HCN1 hyperpolarization-activated cyclic nucleotide-gated channel enhances evoked GABA release from parvalbumin positive interneurons

Tobias Bock, Eric W. Buss, Olivia M. Lofaro, Félix Leroy, Bina Santoro, Steven A. Siegelbaum

This study investigates how HCN1 channels in parvalbumin-positive interneurons regulate GABA release in hippocampal CA1, showing that HCN1 enhances inhibitory transmission.

bioRxiv · Nov 11, 2022 · PreprintNeuroscience

Seizures, behavioral deficits and adverse drug responses in two new genetic mouse models of HCN1 epileptic encephalopathy

Andrea Merseburg, Jacquelin Kasemir, Eric W. Buss, Félix Leroy, Tobias Bock, Alessandro Porro, Anastasia Barnett, Simon E. Tröder, Birgit Engeland, Malte C. Stockebrand, Anna Moroni, Steven A. Siegelbaum, Dirk Isbrandt, Bina Santoro

This study presents two genetic mouse models of HCN1 epileptic encephalopathy, showing seizure susceptibility and adverse drug responses, highlighting the need for tailored therapies.

eLife · Aug 16, 2022Peer-reviewedNeuroscience

Somatic Depolarization Enhances Hippocampal CA1 Dendritic Spike Propagation and Distal Input Driven Synaptic Plasticity

Tobias Bock, Adrian Negrean, Steven A. Siegelbaum

Journal of Neuroscience · Mar 7, 2022Peer-reviewedNeuroscience