Acylation of the RTX Toxin MbxA stimulates host membrane disruption through a specific interaction with cholesterol
Feby Mariam Chacko, Sarah Michelle Ganz, Anne Pfitzer-Bilsing…·Lutz Schmitt
This study investigates how acylation of the RTX toxin MbxA enhances membrane disruption by interacting with cholesterol, showing acylation promotes pore formation but not initial membrane binding.