Author

Feby Mariam Chacko

Heinrich Heine University DüsseldorfORCID 0000-0003-4117-4122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

Anne Pfitzer-Bilsing· 1 shared Arnab Kumar Shau· 1 shared Lutz SchmittiD· 1 shared Marten ExterkateiD· 1 shared Philipp WesthoffiD· 1 shared Sander H. J. SmitsiD· 1 shared Sarah Michelle Ganz· 1 shared Sebastian HänschiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiochemistry

Anne Pfitzer-Bilsing

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2 papers

Recent·Most cited

BiochemistryBiochimica et Biophysica Acta (BBA) - BiomembranesPeer-reviewedNov 27, 2025

Acylation of the RTX Toxin MbxA stimulates host membrane disruption through a specific interaction with cholesterol

Feby Mariam Chacko, Sarah Michelle Ganz, Anne Pfitzer-Bilsing…·Lutz Schmitt

This study investigates how acylation of the RTX toxin MbxA enhances membrane disruption by interacting with cholesterol, showing acylation promotes pore formation but not initial membrane binding.

DOI 10.1016/j.bbamem.2025.184487

experimental assayhost-pathogen & immune response

𝕏 PostBluesky

MicrobiologyCurrent BiologyPeer-reviewedOct 10, 2025

A starvation-triggered AAA+ ATPase halts chromosome replication progression by disassembling the bacterial DNA sliding clamp

Surbhi, Arnab Kumar Shau, Feby Mariam Chacko, Sunish Kumar Radhakrishnan

The paper identifies IncA, a starvation-induced AAA+ ATPase, which halts DNA replication by disassembling the bacterial DNA sliding clamp in Caulobacter crescentus.

1 citation

bacteria (other)DNA methylation

𝕏 PostBluesky