Shoma Nakagawa

Lineage tracing reveals asynchronous fate restriction in mouse embryos and stem cell-derived embryo models

The paper uses lineage tracing to show that fate restriction in mouse embryos and stem cell-derived models is asynchronous and not solely determined by cell identity.

Proteome asymmetry in mouse and human embryos before fate specification

The paper shows proteomic asymmetry in mouse and human embryos that influences lineage segregation.

SMARCAD1 and TOPBP1 contribute to heterochromatin maintenance at the transition from the 2C-like to the pluripotent state

This study identifies SMARCAD1 and TOPBP1 as regulators of heterochromatin maintenance during the transition from 2C-like to pluripotent states in mouse embryos.