Sergi Aranda

This paper shows that extending G1 phase in cancer cells creates a therapeutic window for epigenetic drugs, with LSD1 inhibition and CDK4/6 inhibition working synergistically to induce differentiation and improve survival in AML models.

This study identifies SMARCAD1 and TOPBP1 as regulators of heterochromatin maintenance during the transition from 2C-like to pluripotent states in mouse embryos.

This paper introduces Comp-ChIP-seq, a method to normalize ChIP-seq data across samples, improving reproducibility and reducing variability in genome-wide analysis.