Author

Lucas D. Huffman

University of MichiganORCID 0000-0002-7779-086XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Ashley L. KalinskiiD· 2 shared Craig N. JohnsoniD· 2 shared Daniel H. GeschwindiD· 2 shared Hannah HafneriD· 2 shared Rafi KoheniD· 2 shared Riki KawaguchiiD· 2 shared Roman J. GigeriD· 2 shared Ryan PassinoiD· 2 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Ashley L. KalinskiORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

The Injured Sciatic Nerve Atlas (iSNAT), Insights into the Cellular and Molecular Basis of Neural Tissue Degeneration and Regeneration

Xiaofeng Zhao, Lucas D. Huffman, Hannah Hafner, Mitre Athaiya, Matthew C. Finneran, Ashley L. Kalinski, Rafi Kohen, Corey G. K. Flynn, Ryan Passino, Craig N. Johnson, David C. Kohrman, Riki Kawaguchi, Lynda J.‐S. Yang, Jeffery L. Twiss, Daniel H. Geschwind, , Roman J. Giger

The paper creates an atlas of injured sciatic nerve cells and identifies immune microenvironments and communication networks in mouse nerve regeneration.

eLife · Dec 14, 2022Peer-reviewedNeuroscience

Analysis of the Immune Response to Sciatic Nerve Injury Identifies Efferocytosis as a Key Mechanism of Nerve Debridement

Ashley L. Kalinski, Choya Yoon, Lucas D. Huffman, Patrick C. Duncker, Rafi Kohen, Ryan Passino, Hannah Hafner, Craig N. Johnson, Riki Kawaguchi, Kevin S. Carbajal, Juan Sebastián Jara, Edmund R Hollis II, Daniel H. Geschwind, Benjamin M. Segal, Roman J. Giger

This study identifies efferocytosis as a key mechanism for nerve debridement following sciatic nerve injury through single-cell RNA-sequencing and genetic analysis.

eLife · Dec 2, 2020Peer-reviewedNeuroscience