Author

Mark B. Stoessel

University of Rochester MedicineORCID 0000-0002-7785-2645Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Ania Katarzyna MajewskaiD· 2 shared Brendan S. WhitelawiD· 2 shared Rianne D. StowelliD· 2 shared Adler Guerrero· 1 shared Albert Jiang· 1 shared Alex Donovan· 1 shared Andrea H. BrandiD· 1 shared Andrea Leonard· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersNeuroscience

Ania Katarzyna MajewskaORCID

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3 papers

Recent·Most cited

Purinergic signaling promotes gliomagenesis through nuclear calcium transients

Shuai Wang, Jenna Richter, Claire Kim, Rebecca Ronnen, Julia Cai, Yunfei Song, Sara Haddock, Mark B. Stoessel, Hannah Dada, Suzanne Gross, Adler Guerrero, Theodoris Karnavas, Gabriele Stephan, Greg Belizaire, Luke J. Bonanni, , Dimitris G. Placantonakis

This study identifies purinergic signaling via P2RY1 receptors and nuclear calcium transients as a driver of glioblastoma tumorigenesis, with therapeutic potential through P2RY1 inhibition.

bioRxiv · May 15, 2026 · PreprintCancer Biology

The effects of P2Y12 loss on microglial gene expression, dynamics, and injury response in the cerebellum and cerebral cortex.

Mark B. Stoessel, Rianne D. Stowell, Rebecca L. Lowery, Linh Le, Andy N. Vu, Brendan S. Whitelaw, Ania Katarzyna Majewska

This study investigates how P2Y12 loss affects microglial gene expression, dynamics, and injury response in the cerebellum and cerebral cortex, finding region-specific roles for P2Y12 in injury response and plasticity.

Brain, Behavior, and Immunity · Aug 1, 2025Peer-reviewedNeuroscience

Noradrenergic signaling in wakeful states inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex.

Rianne D. Stowell, Grayson O. Sipe, Ryan P. Dawes, Hanna N. Batchelor, Katheryn A. Lordy, Brendan S. Whitelaw, Mark B. Stoessel, Jean M. Bidlack, Edward Brown, Mriganka Sur, Ania Katarzyna Majewska

Nature Neuroscience · Oct 21, 2019Peer-reviewedNeuroscience