Author

Rachel S. Heise

Cornell UniversityORCID 0000-0002-7785-4579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Ashish SaxenaiD· 1 shared Bobak ParangiD· 1 shared Eric E. GardneriD· 1 shared John BlenisiD· 1 shared Liron YoffeiD· 1 shared Michal J. NagieciD· 1 shared Nasser Khaled AltorkiiD· 1 shared Rabia Khan· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Ashish SaxenaORCID

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1 paper

Recent·Most cited

Propionate metabolism dysregulation promotes drug-tolerant persister cell survival in non-small cell lung cancer

Bobak Parang, Liron Yoffe, Rabia Khan, Zhongchi Li, Michal J. Nagiec, Eric E. Gardner, Yiwey Shieh, Rachel S. Heise, Ashish Saxena, Nasser Khaled Altorki, John Blenis

This study shows that propionate metabolism dysregulation, through MMA accumulation and EMT activation, promotes drug-tolerant persister cell survival in NSCLC.

bioRxiv · Oct 15, 2025 · PreprintCancer Biology