Author

Andrew Kekūpaʻa Knutson

University of California, Santa CruzORCID 0000-0002-7800-0807Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Developmental Biology· 1

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Assay:bulk RNA-seq· 3 Research Focus:differential expression· 3 Approach:statistical model· 3 Organism:C. elegans· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Andreas RechtsteineriD· 2 shared Susan StromeiD· 2 shared Abigail Avelar· 1 shared Francesca PalladinoiD· 1 shared Gaël YvertiD· 1 shared Ralph V. ShohetiD· 1 shared Thea A. Egelhofer· 1 shared Valérie J. P. RobertiD· 1 shared

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2017-2022 · peak 1/yr

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8 top collaborators · 13 mutual co-author links

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2 shared papersGenetics

Andreas RechtsteinerORCID

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3 papers

Recent·Most cited

The ZMYND8 chromatin factor protects cardiomyocyte identity and function in the mouse heart

Andrew Kekūpaʻa Knutson, Abigail Avelar, Ralph V. Shohet

This study shows that ZMYND8 is necessary for maintaining cardiomyocyte gene expression and cardiac function in mice, as its absence leads to cardiomegaly and cardiac dysfunction.

bioRxiv · Oct 6, 2022 · PreprintGenetics

The C. elegans SET-2 histone methyltransferase maintains germline fate by preventing progressive transcriptomic deregulation across generations

Valérie J. P. Robert, Andrew Kekūpaʻa Knutson, Andreas Rechtsteiner, Gaël Yvert, Susan Strome, Francesca Palladino

This study shows that the absence of SET-2 in C. elegans leads to progressive transcriptomic deregulation across generations, resulting in loss of germline identity and sterility.

bioRxiv · Mar 21, 2019 · PreprintGenetics

Germ granules prevent accumulation of somatic transcripts in the adult C. elegans germline

Andrew Kekūpaʻa Knutson, Thea A. Egelhofer, Andreas Rechtsteiner, Susan Strome

This study shows that P granules in C. elegans prevent the accumulation of somatic transcripts in adult germ cells by down-regulating spermatogenesis RNAs and maintaining germ cell fate.

Genetics · Mar 3, 2017Peer-reviewedDevelopmental Biology