Francesca Palladino

The paper shows that SIN-3 coregulator in C. elegans is essential for adapting to different bacterial diets, specifically through vitamin B12-dependent metabolic pathways.

This study shows that loss of SIN-3 in C. elegans disrupts mitochondrial function and metabolism, leading to mitochondrial fragmentation and altered metabolic flux.

This study identifies two distinct SIN3 complexes in C. elegans that regulate germline gene expression and fertility, revealing their role in X-linked gene silencing.

This study shows that reduced H3K4 methylation in C. elegans shortens lifespan and reduces fertility, contradicting previous findings that suggested H3K4 methylation extends lifespan.

The paper shows that auxin treatment in C. elegans activates the UPR to confer resistance to ER stress, highlighting potential confounding effects of auxin in studies using the AID system.

The paper investigates the role of SET1/COMPASS and condensin in meiotic chromosome organization in C. elegans using fluorescence lifetime imaging microscopy.

The paper identifies a physical and functional interaction between CFP-1 and the Sin3 HDAC complex in C. elegans, showing their coordinated regulation of gene expression.

This study shows that the absence of SET-2 in C. elegans leads to progressive transcriptomic deregulation across generations, resulting in loss of germline identity and sterility.