Kalpana Luthra

Immunogenicity and Structure of a Stabilized HIV -1 clade C Env from a Pediatric Elite neutralizer in Complex with an Autologous bnAb

This study investigates the immunogenicity and structure of a clade C HIV-1 Env trimer from a pediatric elite-neutralizer, showing it elicits strong autologous neutralizing antibodies and reveals key neutralizing epitopes.

Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms

This study stabilizes an HIV-1 clade C trimer using multiple platforms and shows improved antigenic and immunogenic properties.

Implications of diabetes mellitus on pathophysiology of Tuberculosis: Role of AGE-RAGE Axis and Glycated Proteins

This study examines how diabetes-induced AGEs and RAGE contribute to immune dysfunction and worsen tuberculosis severity in comorbid patients.

A versatile high throughput strategy for cloning the env gene of HIV-1

This paper describes a high-throughput method for cloning HIV-1 env genes using Phusion polymerase and overlap extension PCR, enabling efficient analysis of diverse env genes from infected individuals.

sFlt-1 commutes unfolded protein response into endoplasmic reticulum stress in trophoblast cells in preeclamptic pregnancies

The paper shows that sFlt-1 from preeclamptic pregnancies induces endoplasmic reticulum stress in trophoblast cells through increased expression of ER stress markers.

sFlt-1 (sVEGFR1) induces placental endoplasmic reticulum stress in trophoblast cell: implications for the complications in preeclampsia - an in vitro study

This study shows that sFlt-1 increases ER stress markers in trophoblast cells, linking it to preeclampsia complications.