Author

Catherine A. Higgins

Queen's University BelfastORCID 0000-0002-7801-9452Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A.R. Phillips· 1 shared Christopher McLaughlin· 1 shared Claudia Hamilton· 1 shared Connor N. BrowniD· 1 shared Daniel B. LongleyiD· 1 shared Declan F. DohertyiD· 1 shared Donna M. SmalliD· 1 shared Emma M. KerriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A.R. Phillips

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1 paper

Recent·Most cited

FLIP is essential for oncogenic KRAS-driven lung cancer

Claudia Hamilton, Shaun Sharkey, Hajrah A. Khawaja, Matilda Downs, Christopher McLaughlin, Connor N. Brown, Declan F. Doherty, Jennifer Fox, Mihaela Pettigrew, Karl T. Butterworth, A.R. Phillips, Donna M. Small, Timothy Harrison, Catherine A. Higgins, Emma M. Kerr, Daniel B. Longley

This study identifies FLIP as a critical survival factor in KRAS-mutant lung cancers, revealing a KRAS-ERK-FLIP axis that protects against apoptosis and suggests FLIP as a therapeutic target.

bioRxiv · Aug 5, 2026 · PreprintCancer Biology