Alexander Crits‐Christoph

This paper develops a scalable transposon mutagenesis system for non-model bacteria, identifying functional configurations and applying them to study gene function in Comamonas testosteroni.

This paper develops a genetic toolkit for Sporosarcina pasteurii, enabling genome modification and uncovering genes involved in biocementation.

This paper develops an automated platform using active learning to discover electroporation protocols for non-model microbes, achieving higher transformation efficiency for industrial chassis.

This study develops genetic tools for Piscinibacter sakaiensis to enable functional genomics and engineering for PET degradation.

The paper identifies functional plasmids for Vibrio natriegens using the POSSUM toolkit, showing compatibility of multiple replicons in wild-type and engineered strains.

Reanalysis of public environmental metatranscriptomes from the Huanan market links SARS-CoV-2 positivity to one wildlife stall containing raccoon dog, civet and bamboo rat genetic material.

This paper develops genome-based models to predict microbial growth conditions using amino acid composition, showing high accuracy for oxygen tolerance, temperature, salinity, and pH.

This study identifies mobile genetic elements and defense systems in Asgard archaea, revealing their role in shaping genetic diversity and evolution.

The paper designs and constructs a pan-microbial genetic toolkit using high-throughput methods to identify functional genetic parts in non-model microbes.

The paper introduces a scalable framework to identify functional origins of replication in non-model bacteria using a combinatorial plasmid library and next-generation sequencing.

The paper uses transporter gene frequencies to predict metabolite characteristics and identifies siderophore-like BGCs in gut microbiomes.