Felipe-Andrés Piedra

RSV & rhinovirus coinfection order dictates outcome via type III interferon-mediated interference in infant respiratory epithelium

This study shows that the order of RSV and RV infection in infants determines disease outcome through type III interferon-mediated viral interference.

RSV Infects the Human Nasal Epithelium via the Basolateral Route with Distinct Subgroup Infectivity and Basal Cell Tropism

This study shows RSV can infect respiratory epithelium via the basolateral route, targeting basal cells, with RSV/B/BA showing higher basolateral infectivity than RSV/A/ON.

Functional genomics in a microbe that degrades and metabolizes PET plastic

This study develops genetic tools for Piscinibacter sakaiensis to enable functional genomics and engineering for PET degradation.

Nasal microbionts differentially colonize and elicit cytokines in human nasal epithelial organoids

This study uses human nasal epithelial organoids to investigate how different bacteria colonize nasal tissue and induce cytokine responses, finding differential effects on chemokines and inflammasome signaling.

Eco-Microbiology: Discovering Biochemical Enhancers of PET Biodegradation by Piscinibacter sakaiensis

This paper identifies biochemical enhancers of PET biodegradation by Piscinibacter sakaiensis using iterative screening and biodegradation assays.

Examining intra-host genetic variation of RSV by short read high-throughput sequencing

The paper analyzes intra-host RSV genetic variation using short-read sequencing, finding low variation but differences between genomic and transcriptomic data.

Oligonucleotide Capture Sequencing of the SARS-CoV-2 Genome and Subgenomic Fragments from COVID-19 Individuals

This study develops an oligonucleotide capture sequencing method to generate SARS-CoV-2 genomic and transcriptome sequences from clinical samples, revealing differential transcriptional activity and ORF10 expression.

Genotype-dependent and non-gradient patterns of RSV gene expression

This study shows RSV gene expression is genotype-dependent and non-gradient, with the G gene consistently more expressed than upstream genes, suggesting a novel transcriptional regulation mechanism involving GS signal N-phase alignment.