Molecular BiologybioRxivPreprint
The SMC5/6 complex is required for maintenance of genome integrity upon APOBEC3A-mediated replication stress
David R O’Leary, Ava R. Hansen, Dylan F. Fingerman…·Abby M. Green
This study identifies the SMC5/6 complex as essential for genome stability in cells with active APOBEC3A, showing that its loss leads to increased DNA damage and replication stress.
DOI 10.1101/2023.11.28.568952