Amog P. Urs

This study compares the effects of tirzepatide and caloric restriction on hematopoiesis in obese mice, finding tirzepatide preserves HSPC cycling and reduces inflammatory monocytes while CR causes cytopenias.

This study identifies circPCMTD1 as a circular RNA that promotes leukemic cell proliferation by enhancing DNA damage response tolerance through a novel peptide product.

This study shows that EGFL7 promotes HSC expansion and survival, and its absence leads to reduced HSPC numbers and increased quiescence, with rEGFL7 treatment reversing these effects.