Nate Cira

This paper introduces a digital droplet microarray system for high-throughput antibiotic tolerance measurement using SPOTs and Poissonian statistics, demonstrating its application to Klebsiella pneumoniae.

This paper introduces a method to precisely load scarce reagents on droplet microarrays, reducing material usage and enabling high-throughput assays with minimal volumes.

EZ-SPOTs provides a cost-effective, reusable liquid handling platform for high-throughput experiments, matching gold standard assays in antibiotic susceptibility testing.

This paper introduces M2D2, a two-stage ML model that identifies synergistic antimicrobial drug combinations and validates them experimentally against E. coli.