Suraj Kannan

The paper uses random survival forests to identify 33 myocardial genes predictive of survival in HFpEF, outperforming clinical parameters in prognosis modeling.

The paper identifies cardiac progenitors as a source of Wnts that regulate second heart field development through secretion, using genetic manipulation and single-cell RNA sequencing in mice.

The paper develops a transcriptomic entropy metric to benchmark maturation of PSC-derived cardiomyocytes against endogenous tissue using scRNA-seq data.

This study shows noncanonical Notch signaling has stage-specific roles in cardiac development, inhibiting early heart formation but promoting later growth.

This study identifies PGC1/PPAR signaling and its regulators Yap1 and SF3B2 as key drivers of cardiomyocyte maturation through single-cell transcriptomic analysis across neonatal to adult hearts.

The paper integrates proteomic and genomic data from skeletal muscle myocytes to identify gene and protein expression differences between slow and fast-twitch fiber types.