Andrew R. Bottrill

This study identifies SFA1's role in coordinating cytoskeletal organisation, apical polarity, and cell replication during Plasmodium sexual development, showing its necessity for parasite transmission.

This study identifies Plasmodium NEK4 as a key regulator that couples meiotic initiation with zygote morphogenesis in malaria parasites.

The paper identifies GAPM2 as an IMC component in Plasmodium species and reveals its heterotrimeric complex structure and functional role in the glideosome.

This study identifies ARK1 as a critical regulator of mitosis in Plasmodium, forming a non-canonical chromosomal passenger complex with divergent INCENPs, and highlights its potential as an antimalarial target.

This study identifies three Plasmodium protein kinases involved in regulating MTOC, kinetochore, and axoneme organisation during male gametogenesis, revealing their substrates and morphological effects.

This study identifies the SUN1-ALLAN complex as critical for coordinating nuclear envelope remodeling and bipartite MTOC segregation during rapid mitosis in Plasmodium male gametogenesis.

This study identifies NEK1's role in organizing the MTOC and ensuring kinetochore attachment during rapid mitosis in Plasmodium male gamete formation.

This study identifies Cdk1-mediated phosphorylation of Sam68 at T33 and T317, showing it reduces RNA binding and alternative splicing activity, promoting cell proliferation and inhibiting apoptosis in HCT116 cells.

This study shows that activating M1 muscarinic receptors with VU846 slows murine prion disease progression, reduces neuroinflammation, and preserves synaptic proteins.

This paper expands the zebrafish genetic code to incorporate three unnatural amino acids into proteins, providing proteomic evidence for their successful integration.