Author

Uma Chandrachud

Harvard UniversityORCID 0000-0002-7848-1102Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2

Frequent Co-Authors

Alessio Vittorio ColomboiD· 1 shared Brandon L. MeyerinkiD· 1 shared Claire E. ShamberiD· 1 shared Elisabeth S. ButziD· 1 shared Janos GrohiD· 1 shared Louis‐Jan PilaziD· 1 shared Luca Montore· 1 shared Madison SangsteriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Alessio Vittorio ColomboORCID

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2 papers

Recent·Most cited

Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover

Seda Yaşa, Elisabeth S. Butz, Alessio Vittorio Colombo, Uma Chandrachud, Luca Montore, Sarah K. Tschirner, Matthias Prestel, Steven D. Sheridan, Stephan A. Müller, Janos Groh, Stefan F. Lichtenthaler, Sabina Tahirović, Susan L. Cotman

This study shows that loss of CLN3 in microglia causes lipid metabolism defects and impaired myelin turnover, leading to early neuroinflammation in a mouse model of CLN3 disease.

Communications Biology · Oct 22, 2024Peer-reviewedNeuroscience

AAV-mediated gene transfer of WDR45 corrects neurologic deficits in the mouse model of beta-propeller protein-associated neurodegeneration

Maria Carla Carisi, Claire E. Shamber, Martha Bishop, Madison Sangster, Uma Chandrachud, Brandon L. Meyerink, Louis‐Jan Pilaz, Yulia Grishchuk

This study shows that AAV-mediated WDR45 gene transfer rescues neurologic deficits and autophagy defects in a mouse model of BPAN.

bioRxiv · Jun 18, 2024 · PreprintNeuroscience