Samantha G. Palace

This paper introduces BASS-GWAS, a Bayesian method for efficient microbial GWAS, identifying causal loci with fewer phenotyped isolates than random sampling.

This study shows that gyrA variants from ciprofloxacin resistance increase zoliflodacin resistance and fitness cost of the gyrB D429N mutation in N. gonorrhoeae.

The paper evaluates the in vitro activity of pairwise antibiotic combinations against Neisseria gonorrhoeae, finding no evidence of antagonism.

The paper uses long-read sequencing to analyze opa gene diversity in Neisseria gonorrhoeae genomes, revealing high variability and rapid evolution of these genes.

This study shows that the gyrBD429N mutation in Neisseria gonorrhoeae confers cross-resistance to gepotidacin and has variable fitness effects across strains.

CLARC refines bacterial ortholog groups by integrating linkage and annotation data, reducing accessory gene estimates and improving evolutionary predictions in Streptococcus pneumoniae.

This study shows that axial asymmetry in Neisseria gonorrhoeae guides orthogonal division planes, maintaining diplococcal morphology through ParB segregation and MinCDE system function.

This study quantifies how antibiotic use and genetic resistance determinants affect bacterial lineage dynamics using a Bayesian model and Neisseria gonorrhoeae isolates.