Alexandra N. Birtasu

This study uses cryo-electron tomography to analyze structural changes in podocytes during anti-nephrin-mediated kidney disease progression.

The paper uses cryo-electron tomography to reveal the native structure of the human slit diaphragm, showing a fishnet-like lattice with 9 nm spacing, more compact than in mice or Drosophila.

The paper identifies in situ structures of gap junctions in C. elegans using cryo-electron tomography and sub-tomogram averaging, revealing a cytosolic cap formed by the stomatin UNC-1 protein.

This study uses cryo-electron tomography to reveal the bi-layered, fishnet-like architecture of the slit diaphragm in Drosophila nephrocytes, linking its structure to function and conservation across species.

This study localizes albumin in kidney tissue using correlative super-resolution light and electron microscopy to map its distribution and quantify concentration gradients across the filtration barrier.