Author

Ryan M. Pearson

University of Maryland, BaltimoreORCID 0000-0002-7857-0973Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrea L. CottinghamiD· 2 shared Alireza Hassani NajafabadiiD· 1 shared Fanny Xu· 1 shared Jace W. JonesiD· 1 shared Jacob R. Shaw· 1 shared Josie D. Rezende· 1 shared Junsik J. SungiD· 1 shared Maureen A. KaneiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBioengineering

Andrea L. CottinghamORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintOct 23, 2026

Mesaconate-Based Polyester Nanoparticles Reveal How Metabolite Isomerism Shapes Polymer Behavior, Macrophage Reprogramming, and Systemic Immunomodulation

Md Mohosin Rana, Andrea L. Cottingham, Sara Kolhatkar…·Ryan M. Pearson

This study creates mesaconate-based polyester nanoparticles that show different immunomodulatory effects in macrophages and improve survival in endotoxemia.

DOI 10.64898/2026.10.22.760948

experimental assaydrug response / drug discovery

𝕏 PostBluesky

BioengineeringMolecular Therapy — Methods & Clinical DevelopmentPeer-reviewedMay 14, 2025

Lipid Nanoparticles from L. meyenii Walp Mitigate Sepsis through Multimodal Protein Corona Formation

Junsik J. Sung, Jacob R. Shaw, Josie D. Rezende…·Ryan M. Pearson

This study identifies lipid nanoparticles from maca that reduce inflammation and improve survival in sepsis models by sequestering pro-inflammatory cytokines and acute phase proteins.

6 citations

mouseproteomics

𝕏 PostBluesky