Author

Alireza Hassani Najafabadi

Terasaki FoundationORCID 0000-0002-8215-4374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Surjendu MaityiD· 3 shared Ali KhademhosseiniiD· 2 shared Danial KhorsandiiD· 2 shared Mehmet R. DokmeciiD· 2 shared Neda MohagheghiD· 2 shared Satoru KawakitaiD· 2 shared Vadim JucaudiD· 2 shared Ahmad RashadiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBioengineering

Surjendu MaityORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mesaconate-Based Polyester Nanoparticles Reveal How Metabolite Isomerism Shapes Polymer Behavior, Macrophage Reprogramming, and Systemic Immunomodulation

Md Mohosin Rana, Andrea L. Cottingham, Sara Kolhatkar, Fanny Xu, Alireza Hassani Najafabadi, Ryan M. Pearson

This study creates mesaconate-based polyester nanoparticles that show different immunomodulatory effects in macrophages and improve survival in endotoxemia.

bioRxiv · Oct 23, 2026 · PreprintBioengineering

Embolization-on-a-chip: Novel Vascularized Liver Tumor Model for Evaluation of Cellular and Cytokine Response to Embolic Agents

Huu Tuan Nguyen, Zuzana Tirpáková, Arne Peirsman, Surjendu Maity, Natashya Falcone, Satoru Kawakita, Keuna Jeon, Danial Khorsandi, Ahmad Rashad, Neda Farhadi, Kalpana Mandal, Menekşe Ermis, Rondinelli Donizetti Herculano, Alireza Hassani Najafabadi, Mehmet R. Dokmeci, , Vadim Jucaud

This paper evaluates novel embolic agents using a vascularized liver tumor-on-a-chip model, finding that DESTH induces tumor cell death and alters cytokine levels and vascular morphology.

Biofabrication · Aug 14, 2025Peer-reviewedBioengineering

Antibody-Free Immunopeptide Nano-Conjugates for Brain-Targeted Drug Delivery in Glioblastoma Multiforme

Saurabh Sharma, David Lee, Surjendu Maity, Prabhjeet Singh, Jay Chadokiya, Neda Mohaghegh, Alireza Hassani Najafabadi, Han‐Jun Kim, Ankit Gangrade, Julia Y. Ljubimova, Amanda Kirane, Eggehard Holler

This paper introduces a BBB-penetrating nanoconjugate for glioblastoma treatment that modulates the PD-1/PD-L1 axis without antibodies, showing improved brain accumulation and immune activation in vitro and in vivo.

Bioconjugate Chemistry · Jul 2, 2025Peer-reviewedImmunology

Modeling Immunosenescence on-a-chip: a platform for cancer vaccine efficacy assessment

Surjendu Maity, Alireza Hassani Najafabadi, Satoru Kawakita, Danial Khorsandi, Can Yilgor, Christopher Jewell, Neda Mohaghegh, Mehmet R. Dokmeci, Ali Khademhosseini, Vadim Jucaud

The paper develops an in vitro platform to assess cancer vaccine efficacy in aging immune systems, showing age-dependent differences in antigen presentation and T cell responses.

bioRxiv · May 14, 2025 · PreprintBioengineering