Shijian Zhang

The paper uses a biotin ligation assay to identify HLA-A2 interactors and finds that MIA3 regulates MHC class I cell surface expression.

This study investigates how truncations of the HIV-1 Env cytoplasmic tail affect Env cleavage, incorporation into virions, and antibody neutralization.

The paper analyzes glycosylation and disulfide bonding of wild-type SARS-CoV-2 spike glycoprotein, finding that Golgi processing leads to complex N-glycans and partial infectivity in a Cys15Phe mutant.

The paper describes the engineering of HIV-1 Env variants enriched in a pretriggered conformation, which are more stable and crosslinkable, aiding in structural and immunogenic studies.

This study investigates the conformational plasticity of the uncleaved HIV-1 Env trimer and its implications for antibody recognition and Env cleavage.

This study uses cryo-EM to reveal two conformational states of the HIV-1 Env precursor, explaining its plasticity and implications for immune response.