Author

Alessandra Qualizza

Dana-Farber Cancer InstituteORCID 0009-0002-2002-503XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:protein design· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amos B. SmithiD· 1 shared Aneta MalesaiD· 1 shared Ashlesha A. Deshpande· 1 shared Bernard K. van der VeeriD· 1 shared Catherine M. VerfaillieiD· 1 shared Frederic Lluı́siD· 1 shared Gert VanmarckeiD· 1 shared Haitao DingiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMolecular Biology

Amos B. SmithORCID

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2 papers

Recent·Most cited

Osmolar modulation drives reversible cell cycle exit and human pluripotent cell differentiation via NF-κB and WNT signaling

Jonathan Sai‐Hong Chui, Teresa Izuel Idoype, Alessandra Qualizza, Rita Pires de Almeida, Lindsey Piessens, Bernard K. van der Veer, Gert Vanmarcke, Aneta Malesa, Paraskevi Athanasouli, Ruben Boon, Joris Vriens, Leo A. van Grunsven, Kian Peng Koh, Catherine M. Verfaillie, Frederic Lluı́s

This study shows that hyperosmolar conditions induce cell cycle exit and differentiation in pluripotent cells through NF-κB and WNT signaling pathways.

Advanced Science · Dec 1, 2023Peer-reviewedDevelopmental Biology

Functional and Highly Crosslinkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation

Hanh T. Nguyen, Alessandra Qualizza, Saumya Anang, Meiqing Zhao, Shitao Zou, Rong Zhou, Qian Wang, Shijian Zhang, Ashlesha A. Deshpande, Haitao Ding, Amos B. Smith, John C. Kappes, Joseph Sodroski

The paper describes the engineering of HIV-1 Env variants enriched in a pretriggered conformation, which are more stable and crosslinkable, aiding in structural and immunogenic studies.

bioRxiv · Sep 27, 2021 · PreprintMolecular Biology