Author

Shuobing Chen

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:protein structure prediction· 2 Assay:cryo-EM· 1 Organism:human· 1 Organism:virus· 1

Frequent Co-Authors

Eden P. GoiD· 2 shared Haitao DingiD· 2 shared Heather DesaireiD· 2 shared John C. KappesiD· 2 shared Joseph SodroskiiD· 2 shared Maolin Lu· 2 shared Robert T. Steinbock· 2 shared Shijian ZhangiD· 2 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersMolecular Biology

Eden P. GoORCID

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3 papers

Recent·Most cited

Structure of an LGR dimer - an evolutionary predecessor of glycoprotein hormone receptors

Zhen Long Gong, Shuobing Chen, Ziao Fu, Brian Kloss, Chi Wang, Jonathan Kim, Oliver B. Clarke, Qing Fan, Wayne A. Hendrickson

The paper presents the cryo-EM structure of a nematode LGR dimer, providing insights into the evolution and function of glycoprotein hormone receptors.

Nature Communications · Nov 28, 2025Peer-reviewedMolecular Biology

Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus (HIV-1) envelope glycoprotein trimer

Shijian Zhang, Kunyu Wang, Wei Li Wang, Hanh T. Nguyen, Shuobing Chen, Maolin Lu, Eden P. Go, Haitao Ding, Robert T. Steinbock, Heather Desaire, John C. Kappes, Joseph Sodroski, Youdong Mao

This study investigates the conformational plasticity of the uncleaved HIV-1 Env trimer and its implications for antibody recognition and Env cleavage.

Journal of Virology · Sep 22, 2021Peer-reviewedMolecular Biology

Structural insights into the conformational plasticity of the full-length trimeric HIV-1 envelope glycoprotein precursor

Shijian Zhang, Wei Li Wang, Shuobing Chen, Maolin Lu, Eden P. Go, Robert T. Steinbock, Haitao Ding, Heather Desaire, John C. Kappes, Joseph Sodroski, Youdong Mao

This study uses cryo-EM to reveal two conformational states of the HIV-1 Env precursor, explaining its plasticity and implications for immune response.

bioRxiv · Mar 25, 2018 · PreprintMicrobiology