Author

Ahmad Alimadadi

Augusta UniversityORCID 0000-0002-7888-5019Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam B. KeetoniD· 1 shared Austin W.T. ChiangiD· 1 shared Catherine C. HedrickiD· 1 shared Catlin Brandle· 1 shared DAVID A. WOLFF· 1 shared Dongwen Lyu· 1 shared Gang ZhouiD· 1 shared Gary Anthony PiazzaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam B. KeetonORCID

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1 paper

Recent·Most cited

Targeting phosphodiesterase 10A disrupts MAPK signaling pathways in the tumor microenvironment to unleash antitumor immunity

Md Yeashin Gazi, Yan Ye, Ogacheko D. Okoko, Xin Wang, Samson Eugin Simon, Ahmad Alimadadi, Nandeeni Suryawanshi, Catlin Brandle, Mei Zheng, Lirong Pei, Khalda Fadlalla, Adam B. Keeton, Yulia Y. Maxuitenko, Xi Chen, Austin W.T. Chiang, , Gang Zhou

This study shows that PDE10A inhibition with ADT-030 suppresses tumor growth by disrupting MAPK signaling and enhancing antitumor immunity through immune cell modulation.

bioRxiv · Feb 28, 2026 · PreprintImmunology