Author
Augusta UniversityORCID 0000-0003-2045-4117Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Samson Eugin Simon, Tiannan Wang, Arsha Sreekumar…·David W. Wolff
This study shows that inhibiting GTP biosynthesis, specifically IMPDH, can suppress Rac1P29S mutant melanoma and enhance responses to MAPK inhibitors.
Fulya Koksalar Alkan, Ahmet B. Çağlayan, Hilmi Kaan Alkan…·Hasan Körkaya
This paper identifies a TGF-β/S100A9/CXCR2 axis in metastatic TNBC that drives neutrophil expansion and immune suppression, with S100A9 loss enhancing immunotherapy response.
Md Yeashin Gazi, Yan Ye, Ogacheko D. Okoko…·Gang Zhou
This study shows that PDE10A inhibition with ADT-030 suppresses tumor growth by disrupting MAPK signaling and enhancing antitumor immunity through immune cell modulation.
Ogacheko D. Okoko, Nada S. Aboelella, Yan Ye…·Gang Zhou
This study shows indomethacin enhances chemo-immunotherapy in mice through both COX-dependent and independent mechanisms, including RAS inhibition.