Nobutake Hosoi

This paper develops a compact promoter for AAV gene therapy targeting inhibitory neurons, showing efficacy in treating epilepsy by restoring GABA function.

This study investigates how mice regulate body resonance and avoidance behavior during whole-body vibration across different axes, revealing axis-specific neuro-musculoskeletal control mechanisms.

This paper develops an AAV vector system with optimized miR.Ts placement to achieve specific and efficient transgene expression in microglia.

This study shows that deletion of class II ARF causes essential tremors by impairing Nav1.6 trafficking to Purkinje cell axon initial segments.