Jennifer K. Logue

Infant CD4 T-cell response to SARS-CoV-2 mRNA vaccination is restricted in cytokine production and modified by vaccine manufacturer

This study compares CD4 T-cell cytokine responses to SARS-CoV-2 mRNA vaccines in infants and adults, finding restricted cytokine production in infants and differences by vaccine type.

SARS-CoV-2 neutralizing antibody specificities differ dramatically between recently infected infants and immune-imprinted individuals

This study compares neutralizing antibody specificities between recently infected infants and immune-imprinted adults, finding distinct targeting of SARS-CoV-2 spike domains.

APMAT analysis reveals the association between CD8 T cell receptors, cognate antigen, and T cell phenotype and persistence

APMAT analysis links CD8 T cell receptors, cognate antigens, and T cell phenotype/persistence using integrated experimental-computational methods.

Generation of antigen-specific paired chain antibody sequences using large language models

This paper introduces MAGE, a model that generates paired human antibody sequences against specific targets, validated against SARS-CoV-2, H5N1, and RSV-A.