Soraia Martins

This study uses NBS patient-derived cerebral organoids to show that impaired p53-mediated DNA damage response contributes to microcephaly by causing neuronal apoptosis and disrupted neurogenesis.

The paper introduces MAGECS, a fast and cost-effective method to select genome-edited cells using magnetic sorting of surface antigens in Cas9-positive cells.

This study uses iPSC-derived neuronal cultures with the TREM2 R47H variant to construct an Aβ-induced gene regulatory network, identifying ER-stress as a potential causal factor in LOAD.

This paper identifies and characterizes human urine-derived renal progenitor cells, revealing their molecular identity, reprogramming potential, and gene regulatory mechanisms for self-renewal and differentiation.