Author

Andreas Müller‐Schiffmann

Heinrich Heine University DüsseldorfORCID 0000-0002-8079-4626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Carsten KorthiD· 2 shared Amanda Macieik· 1 shared Ana Raquel Moreira· 1 shared Anuradha F. LingappaiD· 1 shared Christine Van BroeckhoveniD· 1 shared Claudia MaiosiD· 1 shared Danielle Goldsmith· 1 shared Debendranath DeyiD· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Carsten KorthORCID

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2 papers

Recent·Most cited

Protein Assembly Modulation: A New Approach to ALS Therapeutics

Shao Feng Yu, Kumar Paulvannan, Dennis Solas, Anuradha F. Lingappa, Ana Raquel Moreira, Shriya Sahu, Maya Michon, Amanda Macieik, Danielle Goldsmith, Nicholas DeYarman, Suguna Mallesh, M. Dharma Prasad, Claudia Maios, Kai Ruan, Giulio Srubek Tomassy, , Jeffrey Rosenfeld

This paper introduces a new drug-like small molecule series targeting PDI in a multi-protein complex for ALS treatment, showing activity in cellular and animal models.

Journal of Experimental Neurology · Jan 1, 2024Peer-reviewedNeuroscience

IPSC-derived neuronal cultures expressing the Alzheimer’s disease associated rare TREM2 R47H variant enables the construction of an Aβ-induced gene regulatory network

Soraia Martins, Andreas Müller‐Schiffmann, Lars Erichsen, Martina Bohndorf, Wasco Wruck, Kristel Sleegers, Christine Van Broeckhoven, Carsten Korth, James Adjaye

This study uses iPSC-derived neuronal cultures with the TREM2 R47H variant to construct an Aβ-induced gene regulatory network, identifying ER-stress as a potential causal factor in LOAD.

International Journal of Molecular Sciences · Jun 25, 2020Peer-reviewedNeuroscience