Author

Alain Lamarre

Institut National de la Recherche ScientifiqueORCID 0000-0002-7913-871XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Burkhard LudewigiD· 1 shared Christian W. SiebeliD· 1 shared Dave Maurice De SousaiD· 1 shared Eric PerkeyiD· 1 shared Freddy RadtkeiD· 1 shared Frédéric DuvaliD· 1 shared Ivan MaillardiD· 1 shared Jean‐François DaudeliniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Burkhard LudewigORCID

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1 paper

Recent·Most cited

The Notch signaling pathway is a master regulator of CD8+ T cell exhaustion and differentiation during chronic infection

Dave Maurice De Sousa, Salix Boulet, Frédéric Duval, Eric Perkey, Jean‐François Daudelin, Laure Le Corre, Marie‐Ève Lebel, Alain Lamarre, Freddy Radtke, Burkhard Ludewig, Christian W. Siebel, Ivan Maillard, Nathalie Labrecque

This study shows that Notch signaling regulates CD8+ T cell exhaustion and differentiation during chronic infection by promoting the transition from progenitor to effector-like cells and preventing terminal exhaustion.

bioRxiv · Sep 5, 2026 · PreprintImmunology