Omar de Faria

Myelin basic protein is an RNA chaperone in microglial nuclear retro-transport

The paper identifies myelin basic protein (MBP) as an RNA chaperone that facilitates microglial nuclear import of myelin RNA, with implications for multiple sclerosis pathology.

Constitutive DREADD signalling modulates oligodendrocyte precursor cell bioelectrical membrane properties and fate

This study shows that constitutive DREADD signalling in oligodendrocyte precursor cells alters bioelectrical properties and fate, highlighting a confound in using DREADDs in small cells.

Paranode stability requires UNC5B expression by oligodendrocytes

This study shows that UNC5B in oligodendrocytes is essential for maintaining paranodal junction stability and myelin integrity in the mature CNS.

MicroRNA-223 protects neurons from degeneration in Experimental Autoimmune Encephalomyelitis

The paper identifies miR-223-3p and miR-27a-3p as upregulated in MS models and shows they protect neurons by downregulating glutamate receptor signaling.