Martin Kupiec

The paper identifies a universal mechanism by which cells adapt gene expression to different carbon sources through calcium signaling regulated by glycolytic metabolites and ionic memory of past carbon sources.

This study shows that PCNA unloading is necessary for homologous recombination to occur, even without the Srs2 helicase.

The paper identifies ELG1 as a gene affecting telomere length in yeast and shows SUMOylated PCNA regulates telomerase activity through interactions with the CST complex.

This study shows that S. cerevisiae cells can survive without Pds5 if Mcd1 levels are increased and SUMO-PCNA is elevated, revealing Pds5's role in cohesin stability and DNA replication coordination.

The paper shows that SUMOylation of PCNA represses a recombination-based repair pathway in yeast, which can be counteracted by Elg1 or Rad52.

The paper identifies a mechanism by which PCNA unloading activity coordinates DNA replication with nucleosome assembly to maintain heterochromatin silencing during S-phase.