Author

Grant A. King

Fred Hutch Cancer CenterORCID 0000-0001-9854-3174Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:yeast· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Approach:genetic perturbation / CRISPR· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Elçin ÜnaliD· 2 shared Madison E. WalshiD· 2 shared Benjamin S. StyleriD· 1 shared Cyrus T. RuedigeriD· 1 shared Daniel Chan· 1 shared Danielle M. JorgensiD· 1 shared David Scott BoothiD· 1 shared Eric M. SawyeriD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCell Biology

Elçin ÜnalORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivAug 28, 2026

Tom70-mediated mitochondria-nuclear envelope contacts regulate nuclear pore complex inheritance during gametogenesis

Cyrus T. Ruediger, Benjamin S. Styler, Eric M. Sawyer…·Elçin Ünal

The paper identifies Tom70 as a regulator of nuclear pore complex exclusion during gametogenesis in yeast by mediating mitochondria-nuclear envelope contacts.

3 citations

yeastgenetic perturbation / CRISPR

𝕏 PostBluesky

Cell BiologybioRxivPreprintMay 14, 2025

A Conserved Disruption of the Nuclear Permeability Barrier in Meiosis is Controlled by a Kinase-Phosphatase Pair in Saccharomyces cerevisiae

Madison E. Walsh, Keerthana Chetlapalli, Srigokul Upadhyayula…·Elçin Ünal

The paper identifies a conserved meiotic mechanism called virtual nuclear envelope breakdown (vNEBD) in yeast, regulated by Ime2 kinase and Gip1 phosphatase.

DOI 10.1101/2025.05.14.654091

yeastgenetic perturbation / CRISPR

𝕏 PostBluesky

GeneticsbioRxivPreprintAug 31, 2018

Glycosyltransferases promote development and prevent promiscuous cell aggregation in the choanoflagellate S. rosetta

Laura A. Wetzel, Tera C. Levin, Ryan E. Hulett…·Nicole King

The paper identifies glycosyltransferase mutations causing defective rosette development and promiscuous cell aggregation in S. rosetta, suggesting an ancient role in development and multicellularity regulation.

1 citation

experimental assay

𝕏 PostBluesky

GeneticsProceedings of the National Academy of SciencesPeer-reviewedFeb 13, 2018

Pivotal roles of PCNA loading and unloading on heterochromatin function

Ryan Janke, Grant A. King, Martin Kupiec, Jasper Rine

The paper identifies a mechanism by which PCNA unloading activity coordinates DNA replication with nucleosome assembly to maintain heterochromatin silencing during S-phase.

45 citations

yeastDNA methylation

𝕏 PostBluesky