Bo Liu

SEEKER screens TCR-pMHC combinations to identify antigen recognition, finding polyreactive T cells recognizing up to 80 autoantigens in autoimmune disease.

SHERRY2 is a single-cell RNA sequencing protocol that improves sensitivity and accuracy by eliminating second-strand cDNA synthesis, outperforming existing methods in detecting low-abundance transcripts and specific gene functions.

scASK is an ensemble framework for classifying cell types from scRNA-seq data, achieving better accuracy and robustness than existing methods.