Author

Eugene Tkachenko

University of California San DiegoORCID 0000-0002-7964-484XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Alex Groisman· 2 shared Edgar Gutierrez· 2 shared Alex A. Chenchik· 1 shared Ararat J. AbloogluiD· 1 shared Bart G. M. W. WeijtsiD· 1 shared Benjamin B. YelleniD· 1 shared David J. TraveriD· 1 shared Debbie Deng· 1 shared

Activity by Year

2016-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersDevelopmental Biology

Alex Groisman

Mutual co-authors in cluster

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3 papers

Recent·Most cited

cloneXplorer: A high-throughput clone discovery platform based on conical microwell arrays

Guido Stadler, Eugene Tkachenko, Oscar Neri, Michael Zakharov, Orr Zohar, Debbie Deng, Kitt D. Paraiso, Hajar Rajaei, Shaun P. Steele, Xiling Shen, Alex A. Chenchik, Benjamin B. Yellen

The paper introduces cloneXplorer, a platform for generating antigen-specific T cell clones from peripheral blood using conical microwell arrays, and demonstrates its ability to identify and isolate functionally defined T cells.

bioRxiv · Jan 20, 2026 · PreprintCell Biology

Blood flow-induced Notch activation and endothelial migration enable embryonic vascular remodeling.

Bart G. M. W. Weijts, Edgar Gutierrez, Semion K. Saikin, Ararat J. Ablooglu, David J. Traver, Alex Groisman, Eugene Tkachenko

The paper shows that blood flow direction determines endothelial cell fate during vascular remodeling, with venous flow promoting vein formation and arterial flow preventing it.

bioRxiv · Jul 9, 2018 · PreprintDevelopmental Biology

Rigidity of silicone substrates controls cell spreading and stem cell differentiation

Grigory Vertelov, Edgar Gutierrez, Sin-Ae Lee, Edward Ronan, Alex Groisman, Eugene Tkachenko

This study investigates how the rigidity of silicone substrates affects cell spreading and stem cell differentiation, resolving conflicting findings about the role of substrate elasticity versus porosity.

Scientific Reports · Sep 21, 2016Peer-reviewedCell Biology