David J. Myung

CRISPR-Cas13d-mediated targeting of a context-specific essential gene enables selective elimination of uveal melanoma

The paper identifies RASGRP3 as a context-specific essential gene in uveal melanoma and develops a CRISPR-Cas13d RNA-targeting therapeutic that selectively eliminates uveal melanoma cells.

Multidirectional alignment of collagen fibers to guide cell orientation in 3D-printed tissue

This paper develops a method to create 3D-printed collagen scaffolds with controlled fiber alignment patterns to guide cell orientation.

Reinforcement of Fibrillar Collagen Hydrogels with Bioorthogonal Covalent Crosslinks

This paper develops a method to reinforce collagen hydrogels with bioorthogonal covalent crosslinks while preserving their fibrillar structure for tissue engineering.

In Situ UNIversal Orthogonal Network (UNION) Bioink Deposition for Direct Delivery of Corneal Stromal Stem Cells to Corneal Wounds

This paper develops a collagen bioink for delivering corneal stem cells to wounds, promoting transparency and re-epithelialization in a rabbit model.

Interpenetrating networks of fibrillar and amorphous collagen promote cell spreading and hydrogel stability

This paper introduces an interpenetrating collagen network that supports cell spreading while maintaining hydrogel stability by combining fibrillar and amorphous collagen structures.