Author

Christina Spilker

Leibniz Institute for NeurobiologyORCID 0000-0002-7996-7673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Anna KarpovaiD· 2 shared Guilherme M. GomesiD· 2 shared Michael R. KreutziD· 2 shared PingAn YuanxiangiD· 2 shared Rajeev RamaniD· 2 shared Anja Maria OelschlegeliD· 1 shared Antonio Virgilio FaillaiD· 1 shared Carsten ReißneriD· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Anna KarpovaORCID

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2 papers

Recent·Most cited

NeuroscienceThe EMBO JournalPeer-reviewedJan 3, 2023

Preventing Jacob-induced transcriptional inactivation of CREB protects synapses from β-amyloid in Alzheimer's Disease

Katarzyna M. Grochowska, Guilherme M. Gomes, Rajeev Raman…·Michael R. Kreutz

The paper shows that Nitarsone prevents Aβ-induced CREB inactivation and synaptic loss in AD models by blocking Jacob-mediated signalosome assembly.

32 citationstop 3%

mouseexperimental assay

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedNov 29, 2019

SIPA1L2 controls trafficking and signaling of TrkB-containing amphisomes at presynaptic terminals

Maria Andres‐Alonso, Mohamed Raafet Ammar, Ioana Butnaru…·Michael R. Kreutz

This study shows SIPA1L2 connects TrkB-containing amphisomes to dynein for retrograde trafficking and local signaling at presynaptic terminals, essential for BDNF-dependent plasticity.

88 citationstop 2%

mouseexperimental assay

𝕏 PostBluesky