Investigating the Conformational Flexibility of Staphylokinase Across Multiple Time Scales
Anthony P. Legrand, Linda Kasiarova, Naina Verma, Jan Mičan, Joan Planas-Iglesias, Pavel Kohout, Alan Strunga, Josef Kučera, Tomas Henek, Pavel Vaňáček, Tim de Martines, Pavel Kadeřávek, Lukáš Žı́dek, Jiřı́ Damborský, Stanislav Mazurenko, , Martin Marek
This study investigates the conformational flexibility of staphylokinase variants to explain their reduced immunogenicity and altered properties.
bioRxiv · Feb 6, 2026 · PreprintBiochemistry