Author

Linda Kasiarova

Masaryk UniversityORCID 0000-0002-8701-3554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:protein structure· 2 Assay:metagenomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Jiřı́ DamborskýiD· 2 shared Lenka HernychováiD· 2 shared Martin MarekiD· 2 shared Naina VermaiD· 2 shared Tomas HenekiD· 2 shared Alan StrungaiD· 1 shared Anthony P. LegrandiD· 1 shared David BednářiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Jiřı́ DamborskýORCID

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Author profile →

3 papers

Recent·Most cited

Open or closed? Exploring the conformational heterogeneity of human plasminogen across multiple resolution scales

Linda Kasiarova, Naina Verma, Matyáš Pinkas, Tomas Henek, Tomáš Klumpler, Marie Chovančíková, Helena Reutova, Petr Kašpárek, Martina Hlozankova, Jiřı́ Damborský, Jiří Nováček, Lenka Hernychová, Martin Marek

This study characterizes the conformational states of human plasminogen using structural biology techniques, revealing closed and open conformations in recombinant and plasma-derived variants.

bioRxiv · Jul 23, 2026 · PreprintBiochemistry

Investigating the Conformational Flexibility of Staphylokinase Across Multiple Time Scales

Anthony P. Legrand, Linda Kasiarova, Naina Verma, Jan Mičan, Joan Planas-Iglesias, Pavel Kohout, Alan Strunga, Josef Kučera, Tomas Henek, Pavel Vaňáček, Tim de Martines, Pavel Kadeřávek, Lukáš Žı́dek, Jiřı́ Damborský, Stanislav Mazurenko, , Martin Marek

This study investigates the conformational flexibility of staphylokinase variants to explain their reduced immunogenicity and altered properties.

bioRxiv · Feb 6, 2026 · PreprintBiochemistry

Global Analysis by LC-MS/MS of N6-Methyladenosine and Inosine in mRNA Reveals Complex Incidence

Stanislav Stejskal, Veronika Rájecká, Helena Covelo Molares, Ketty Sinigaglia, Květoslava Brožinová, Linda Kasiarova, Michaela Dohnálková, Paul Eduardo Reyes‐Gutierrez, Hana Cahová, Liam P. Keegan, Mary A. O’Connell, Štěpánka Vaňáčová

This paper develops a method to detect and quantify mRNA modifications like m6A, m6Am, and m1A in human RNA, revealing FTO's role in m6Am and ALKBH5's effect on inosine levels.

RNA · Jan 2, 2025Peer-reviewedMolecular Biology