Petr Halada

HelD is a Global Transcription Factor Enhancing Gene Expression in Rapidly Growing Mycobacteria

The paper identifies HelD as a transcription factor that enhances gene expression in rapidly growing mycobacteria and reduces it in stationary phase, with implications for rifampicin resistance.

Expanding the CarD interaction network: CrsL is a novel transcription factor in Mycobacterium smegmatis

This study identifies CrsL as a novel transcription factor in Mycobacterium smegmatis that interacts with CarD and regulates gene expression related to stress adaptation.

Stem-loop induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control

The paper identifies a stem-loop and modified adenines in the uORF2/ATF4 overlap that regulate ATF4 translation under stress, revealing a more complex mechanism than previously thought.

Mycobacterial HelD is a nucleic acids-clearing factor for RNA polymerase

This study identifies HelD as a nucleic acids-clearing factor for RNA polymerase in Mycobacterium smegmatis, revealing its role in recycling RNA polymerase by preventing non-specific DNA interactions and dissociating elongation complexes.