Author

Tim de Martines

Masaryk University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:multiome· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

David BednářiD· 2 shared Jiřı́ DamborskýiD· 2 shared Lenka HernychováiD· 2 shared Martin MarekiD· 2 shared Naina VermaiD· 2 shared Zbyněk ProkopiD· 2 shared Alan StrungaiD· 1 shared Amel Aziba· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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2 shared papersBiochemistry

David BednářORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural mechanism governing radiationless energy transfer in Renilla bioluminescence

Daniel Pluskal, Martin Toul, Naina Verma, Anna Smrčková, Tadeja Gao, Tomáš Buryška, Tim de Martines, Jana Horackova, Marketa Stuchla, Veronika Novakova, Michal Nemergut, Yves Louis Janin, Andrew J. deMello, Stavros Stavrakis, Martin Vácha, , Martin Marek

This study reports co-crystal structures of a bioluminescent energy-transfer complex in Renilla reniformis, revealing the spatial arrangement of donor-acceptor chromophores and their role in efficient radiationless energy transfer.

bioRxiv · Sep 3, 2026 · PreprintBiochemistry

Investigating the Conformational Flexibility of Staphylokinase Across Multiple Time Scales

Anthony P. Legrand, Linda Kasiarova, Naina Verma, Jan Mičan, Joan Planas-Iglesias, Pavel Kohout, Alan Strunga, Josef Kučera, Tomas Henek, Pavel Vaňáček, Tim de Martines, Pavel Kadeřávek, Lukáš Žı́dek, Jiřı́ Damborský, Stanislav Mazurenko, , Martin Marek

This study investigates the conformational flexibility of staphylokinase variants to explain their reduced immunogenicity and altered properties.

bioRxiv · Feb 6, 2026 · PreprintBiochemistry

RNA-mediated MYC multimerization suppresses innate immune signaling

Leonie Uhl, Amel Aziba, Sinah Löbbert, Timothy J. Russell, Toshitha Kannan, Omkar Rajendra Valanju, Christina Schülein-Völk, Tim de Martines, Francisco Montesinos, Michael Bolz, Giacomo Cossa, Theresa Endres, Daniel Solvie, Bastian Krenz, Hans Michael Maric, , Martin Eilers

This study shows that MYC multimerization driven by RNA binding suppresses innate immune signaling by promoting exosome recruitment to R-loops and preventing immunogenic RNA accumulation.

bioRxiv · Dec 6, 2024 · PreprintMolecular Biology